Author

I. Pedroza-Pacheco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

P. Borrow· 2 shared A. Bridgeman· 1 shared A. Townsend· 1 shared A. Vaughan-Jackson· 1 shared H. Borrmann· 1 shared H. Drakesmith· 1 shared J. A. McKeating· 1 shared J. Frost· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

P. Borrow

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

H. Borrmann, R. Davies, M. Dickinson, I. Pedroza-Pacheco, M. Schilling, A. Vaughan-Jackson, W. James, P. Balfe, P. Borrow, J. A. McKeating, X. Zhuang

This study shows that REV-ERB agonists inhibit HIV-1 replication by suppressing its promoter activity in multiple cell types.

Scientific Reports · Aug 6, 2020Peer-reviewedMicrobiology

cGAMP loading enhances the immunogenicity of VLP vaccines

L. Chauveau, A. Bridgeman, T. K. Tan, R. Beveridge, J. Frost, I. Pedroza-Pacheco, T. Partridge, P. Borrow, H. Drakesmith, A. Townsend, J. Rehwinkel

This study shows that incorporating cGAMP into virus-like particles (VLPs) enhances their immunogenicity, leading to stronger T cell responses and antibody titres against HIV and influenza viruses.

bioRxiv · Jan 3, 2020 · PreprintImmunology