Author

L. Chauveau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Rehwinkel· 3 shared A. Bridgeman· 2 shared G. Fowler· 2 shared J. Hertzog· 2 shared A. Komarova· 1 shared A. Solovyov· 1 shared A. Townsend· 1 shared B. Greenbaum· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

J. Rehwinkel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A co-opted endogenous retroviral envelope promotes cell survival by controlling SLC31A1/CTR1-mediated copper transport and homeostasis

S. Tury, L. Chauveau, V. Courgnaud, J.-L. Battini

The paper identifies Refrex1, an endogenous retroviral envelope protein, as a regulator of copper homeostasis through interaction with SLC31A1/CTR1, demonstrating its role in cell survival by controlling copper levels and redox balance.

bioRxiv · Dec 9, 2021Microbiology

The RNA sensor MDA5 detects SARS-CoV-2 infection

N. G. Sampaio, L. Chauveau, J. Hertzog, A. Bridgeman, G. Fowler, J. P. Moonen, M. Dupont, R. A. Russel, M. Noerenberg, J. Rehwinkel

The paper identifies MDA5 as a cellular sensor for SARS-CoV-2 infection that induces type I and III interferons in Calu-3 cells.

bioRxiv · Mar 26, 2021Immunology

Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS

J. Hertzog, W. Zhou, R. E. Rigby, G. Fowler, C. Cursi, L. Chauveau, T. Davenne, P. J. Kranzusch, J. Rehwinkel

This study identifies ORF9 as a VZV protein that inhibits the cGAS/STING pathway, reducing type I IFN production during infection.

bioRxiv · Feb 11, 2020Immunology

cGAMP loading enhances the immunogenicity of VLP vaccines

L. Chauveau, A. Bridgeman, T. K. Tan, R. Beveridge, J. Frost, I. Pedroza-Pacheco, T. Partridge, P. Borrow, H. Drakesmith, A. Townsend, J. Rehwinkel

This study shows that incorporating cGAMP into virus-like particles (VLPs) enhances their immunogenicity, leading to stronger T cell responses and antibody titres against HIV and influenza viruses.

bioRxiv · Jan 3, 2020 · PreprintImmunology

Y-RNAs Lead an Endogenous Program of RIG-I Agonism Mobilized upon RNA Virus Infection and Targeted by HIV

N. Vabret, V. Najburg, A. Solovyov, P. Sulc, S. Balan, G. Beauclair, M. Chazal, H. Varet, R. Legendre, O. Sismeiro, R. Sanchez David, C. McClain, R. Gopal, L. Chauveau, O. Schwartz, , A. Komarova

This study identifies Y-RNAs as endogenous RIG-I ligands that are targeted by HIV through DUSP11 downregulation, enhancing their immunogenicity and triggering antiviral responses.

bioRxiv · Sep 18, 2019Immunology