Author

I. X. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

P. Arvan· 2 shared A. Arunagiri· 1 shared A. Hermann· 1 shared A. Lietzke· 1 shared A. M. Stendahl· 1 shared A. Renberg· 1 shared B. A. Kaufman· 1 shared B. Thompson· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

P. Arvan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential roles of beta-cell IP3R and RyR ER Ca2+ channels in ER stress-induced alterations of beta-cell Ca2+ homeostasis

I. X. Zhang, A. Hermann, J. Leon, A. Arunagiri, P. Arvan, L. Satin

This study investigates how ER stress affects IP3R and RyR Ca2+ channels in beta cells, showing RyR1 dysfunction contributes to Ca2+ dysregulation and apoptosis.

bioRxiv · Oct 11, 2022 · PreprintPhysiology

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

G. L. Pearson, E. M. Walker, N. Lawlor, A. Lietzke, V. Sidarala, J. Zhu, T. Stromer, E. C. Reck, A. M. Stendahl, J. Li, E. Levi-D'Ancona, M. B. Pasmooij, D. L. Hubers, A. Renberg, K. Mohamed, , S. A. Soleimanpour

This study shows that mitochondrial dysfunction triggers a retrograde signaling program that reduces cellular maturity in metabolic tissues, and blocking this signaling can restore cell identity and improve hyperglycemia.

bioRxiv · Aug 2, 2022 · PreprintCell Biology

The effect of macromolecular crowding on single-round transcription by E. coli RNA polymerase

S. Chung, E. Lerner, Y. Jin, S. Kim, Y. Alhadid, L. W. Grimaud, I. X. Zhang, C. M. Knobler, W. M. Gelbart, S. Weiss

This study investigates how macromolecular crowding affects single-round transcription by E. coli RNA polymerase, finding unexpected enhancements in kinetics with large crowders.

bioRxiv · Nov 12, 2017Biochemistry