Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
Adam Caccavano, Anna Vlachos, Nadiya McLean, Sarah Kimmel, June Hoan Kim, Geoffrey A. Vargish, Vivek Mahadevan, Lauren T. Hewitt, Anthony M. Rossi, Ilona Spineux, Sherry Jingjing Wu, Elisabetta Furlanis, Min Dai, Brenda Leyva Garcia, Yating Wang, , Chris J. McBain
The paper shows that opioids suppress inhibition in hippocampal PV-INs but not neocortex across species and development, highlighting conserved and divergent roles in neural circuits.
bioRxiv · Jan 20, 2024Neuroscience