Discrete interneuron subsets participate in GluN1/GluN3A excitatory glycine receptor (eGlyR)-mediated regulation of hippocampal network activity throughout development and evolution.
June Hoan Kim, Anna Vlachos, Vivek Mahadevan, Adam Caccavano, Tue G. Banke, Oliver Crawley, Ana I. Navarro, Xiaoqing Q Yuan, Daniel T. Abebe, Steven Hunt, Geoffrey A. Vargish, Ramesh Chittajallu, Mark A. G. Eldridge, Reza Azadi, Alex C. Cummins, , Kenneth A. Pelkey
The paper shows that eGlyRs in hippocampal interneurons regulate network activity through developmental and evolutionary conserved mechanisms.
bioRxiv · Sep 24, 2025 · PreprintNeuroscience