Author

Romain Merceron

Ghent University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Jan FélixiD· 2 shared Savvas N. SavvidesiD· 2 shared Yehudi BlochiD· 2 shared Ahmad Reza MehdipouriD· 1 shared Alba Sanz-Sanjuan· 1 shared Álvaro Furones Cuadrado· 1 shared Danielle M. ClancyiD· 1 shared Dirk Elewaut· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Jan FélixORCID

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Author profile →

2 papers

Recent·Most cited

Themis and Grb2 form a constitutive structural hub in T cell receptor signalling

Danielle M. Clancy, Alba Sanz-Sanjuan, Elisabeth Gilis, Peter Tougaard, Imke Velghe, Yana Van Droogenbroeck, Jan Félix, Yehudi Bloch, Álvaro Furones Cuadrado, Romain Merceron, Stephan Schenck, Peter Vandenabeele, Janine D. Brunner, Tom Taghon, Dirk Elewaut, Savvas N. Savvides

This study determines the cryo-EM structure of the Themis-Grb2 complex, revealing its role as a dynamic structural hub in T cell receptor signaling and its functional importance in T cell development.

bioRxiv · Feb 16, 2025 · PreprintImmunology

Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23

Yehudi Bloch, Jan Félix, Romain Merceron, Mathias Provost, Royan Alipour Symakani, Robin De Backer, Elisabeth Lambert, Ahmad Reza Mehdipour, Savvas N. Savvides

The paper reports cryo-EM structures of fully assembled IL-12/IL-23 receptor complexes, revealing structural insights and differences in their interactions with receptors.

Nature Structural & Molecular Biology · Jan 29, 2024Peer-reviewedMolecular Biology