Distinct dopamine circuits transmit the reinforcing and anxiogenic effects of nicotine
Claire Nguyen, Sarah Mondoloni, Tinaïg Le Borgne, Ines Centeno, Maxime Côme, Joachim Jehl, Clément Solié, Lauren M. Reynolds, Romain Durand-de Cuttoli, Stéfania Tolu, Sébastien Valverde, Steve Didienne, Bernadette Hannesse, Jean-François Fiancette, Stéphanie Pons, , Philippe Fauré
This study identifies distinct dopamine circuits in the ventral tegmental area that mediate nicotine's reinforcing and anxiogenic effects through opposing responses in neurons projecting to the nucleus accumbens and amygdala.
Neuron · Jul 8, 2021Peer-reviewedNeuroscience