Author

Jean‐Pierre Hardelin

Centre National de la Recherche ScientifiqueORCID 0000-0002-1815-7909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 1

Frequent Co-Authors

Alexandre MourotiD· 3 shared Fabio MartiiD· 3 shared Philippe FauréiD· 3 shared Claire NguyeniD· 2 shared Clément SoliéiD· 2 shared Joachim JehliD· 2 shared Lauren M. ReynoldsiD· 2 shared Sarah MondoloniiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Alexandre MourotORCID

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3 papers

Recent·Most cited

The interpeduncular nucleus blunts the rewarding effect of nicotine

Joachim Jehl, Maria Ciscato, Éléonore Vicq, Nicolas Guyon, Gabrielle Dejean de la Bâtie, Sarah Mondoloni, Jacinthe Frangieh, Monir Mohayyaei, Claire Nguyen, Stéphanie Pons, Uwe Maskos, Jean‐Pierre Hardelin, Fabio Marti, Pierre‐Jean Corringer, Philippe Fauré, Alexandre Mourot

This study shows that the interpeduncular nucleus (IPN) regulates nicotine reward by modulating VTA neuron activity through β4-containing nAChRs.

Neuron · Jun 1, 2025Peer-reviewedNeuroscience

Dopaminergic mechanisms of dynamical social specialization in mouse microsocieties

Clément Solié, A. Nicolson, R. Justo, Yasmine Layadi, B. Morin, Clarisse Batifol, Lauren M. Reynolds, Tinaïg Le Borgne, Sophie L. Fayad, Aylin Gulmez, Jeanne Allegret--Vautrot, Fabrice de Chaumont, Cécile Viollet, Steve Didienne, N. Debray, , Philippe Fauré

This study shows that dopaminergic activity in the ventral tegmental area shapes social roles and labor division in mouse triads through competitive and cooperative strategies.

bioRxiv · Feb 10, 2025 · PreprintNeuroscience

Distinct dopamine circuits transmit the reinforcing and anxiogenic effects of nicotine

Claire Nguyen, Sarah Mondoloni, Tinaïg Le Borgne, Ines Centeno, Maxime Côme, Joachim Jehl, Clément Solié, Lauren M. Reynolds, Romain Durand-de Cuttoli, Stéfania Tolu, Sébastien Valverde, Steve Didienne, Bernadette Hannesse, Jean-François Fiancette, Stéphanie Pons, , Philippe Fauré

This study identifies distinct dopamine circuits in the ventral tegmental area that mediate nicotine's reinforcing and anxiogenic effects through opposing responses in neurons projecting to the nucleus accumbens and amygdala.

Neuron · Jul 8, 2021Peer-reviewedNeuroscience