Upstream translation initiation expands the coding capacity of segmented negative-strand RNA viruses
Elizabeth Sloan, Marta Alenquer, Liliane Man Wah Chung, Sara Clohisey, Adam M. Dinan, Robert James Gifford, Quan Gu, Nerea Irigoyen, Joshua D. Jones, Ingeborg van Knippenberg, Veronica V. Rezelj, Bo Wang, Helen M. Wise, Maria João Amorim, John Kenneth Baillie, , Edward C. Hutchinson
This study shows segmented negative-strand RNA viruses use upstream translation initiation to expand their coding capacity through non-AUG initiation and host mRNA leader sequence appropriation.
bioRxiv · Oct 8, 2019 · PreprintMolecular Biology