Edward C. Hutchinson

The paper introduces Flu Mutation Explorer, a web tool that integrates IAV genomic data with mutation annotations to help interpret host adaptation mutations.

The paper investigates the emergence of the influenza A/H3N2 K subclade, finding limited antigenic change and age-dependent vaccine responses, suggesting non-antigenic selection pressures.

This study shows that avian H5N1 viruses can infect mammary tissue from three cattle breeds, highlighting the risk of viral transmission through milk and the need for cattle inclusion in H5N1 surveillance.

This study identifies HAT and swAT as proteases that activate ICV and IDV HEF proteins, showing that protease specificity does not restrict IDV replication in the human upper respiratory tract.

This study defines the molecular architecture of Influenza A virions using structural and compositional approaches, revealing unique features of filamentous virions.

This study identifies H5 influenza virus infections in vampire bats, showing their potential to spread the virus between marine and terrestrial ecosystems.

This study shows influenza A viruses induce tunnelling nanotube-like structures through apoptosis to spread between cells, evading immune responses.

This study shows SARS-CoV-2 restricts coinfection of individual cells through superinfection exclusion, limiting genetic exchange opportunities and shaping viral evolution.

The paper identifies cryptic proteins from deletion-containing viral genomes that inhibit influenza virus replication and expand its proteome.

The paper develops an interactive 3D tool to explain SARS-CoV-2 spike protein mutations and variants, showing it improves public understanding compared to existing resources.

FISHtoFigure is a software tool for analysing smFISH data, enabling automated spatial analysis of mRNA expression without requiring bioinformatics expertise.

This study shows segmented negative-strand RNA viruses use upstream translation initiation to expand their coding capacity through non-AUG initiation and host mRNA leader sequence appropriation.