Author

Isabelle Douglas

University of Washington

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Aiden F EnoiD· 1 shared Ally Xinyi Kong· 1 shared Haiwei GuiD· 1 shared James W. MacDonaldiD· 1 shared Jinhua Chi· 1 shared Julia Yue CuiiD· 1 shared Khoa Trong Pham· 1 shared Leonardo Diaz· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 paper

Recent·Most cited

Butyrate rescues chlorpyrifos-induced social deficits through inhibition of class I histone deacetylases

Leonardo Diaz, Ally Xinyi Kong, Ping Zhang, Jinhua Chi, Khoa Trong Pham, Maja Johnson, Aiden F Eno, Isabelle Douglas, Yuxuan Mao, James W. MacDonald, Julia Yue Cui, Theo K. Bammler, Haiwei Gu, Yijie Geng

The paper shows that butyrate rescues CPF-induced social deficits in zebrafish by inhibiting class I HDACs, linking CPF exposure to gut microbiome, metabolome, and epigenetic changes.

bioRxiv · Oct 19, 2025 · PreprintNeuroscience