Author

J R Spence

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alyssa J. MilleriD· 1 shared Andrea García GonzáleziD· 1 shared Andrés Marco Giménez· 1 shared Craig N. JohnsoniD· 1 shared Francesca Sgualdino· 1 shared Gauri Patel· 1 shared Hans C. CleversiD· 1 shared Idse HeemskerkiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Alyssa J. MillerORCID

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2 papers

Recent·Most cited

A robust human airway organoid platform enables scalable expansion and trajectory mapping of pulmonary neuroendocrine cells

Noah Candeli, Lisanne den Hartigh, Nicholas Y. Hou, Andrés Marco Giménez, Jose Antonio Sanchez-Villacana, Andrea García González, Shashank Gandhi, Francesca Sgualdino, Alyssa J. Miller, J R Spence, Susana Chuva de Sousa Lopes, José L. McFaline‐Figueroa, Hans C. Clevers, Talya L. Dayton

This paper develops a human airway organoid platform to expand and map the differentiation trajectories of pulmonary neuroendocrine cells.

bioRxiv · Feb 3, 2026 · PreprintDevelopmental Biology

Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

Kyoung Jo, Zong-Yuan Liu, Gauri Patel, Zhiyuan Yu, LiAng Yao, Seth Teague, Craig N. Johnson, J R Spence, Idse Heemskerk

This study identifies FGF-dependent ERK signaling as critical for PS-like differentiation in 2D human gastruloids, driven by FGF4/17 and modulated by FGF8.

Development · Jan 12, 2026Peer-reviewedDevelopmental Biology