Author

Jürgen Brück

Johannes Gutenberg University Mainz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Matthias MiedereriD· 2 shared Alexander MuikiD· 1 shared Aniello FedericoiD· 1 shared Aron Kwiatkowski· 1 shared Ayline KübleriD· 1 shared Benedikt KlaseniD· 1 shared Dominik SchauenburgiD· 1 shared Eliana StanganelloiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Matthias MiedererORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 11, 2026

Lung-targeted cytokine-coding RNA-lipoplexes induce T and NK cell-mediated anti-tumor immune response

Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin

This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.

DOI 10.64898/2026.05.06.723126

mousebulk RNA-seq

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Cancer BiologyEJNMMI ResearchPeer-reviewedFeb 5, 2026

Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography

Jürgen Brück, Dominik Schauenburg, Seah Ling Kuan…·Matthias Miederer

This paper develops a PET-based method to visualize pH changes in the tumor microenvironment using [18F]FDG-4MBA, showing it can detect small pH differences in different tumors in the same mouse.

1 citation

mouseimaging

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