Author

J. A. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

B. P. Kleinstiver· 1 shared C. Fernandez-del Castillo· 1 shared C. Shiau· 1 shared D. Gong· 1 shared D. T. Ting· 1 shared G. B. Robb· 1 shared H. E. Stutzman· 1 shared H. Roberts· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

B. P. Kleinstiver

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis

C. Shiau, J. Cao, M. T. Gregory, D. Gong, X. Yin, J.-W. Cho, P. L. Wang, J. Su, S. Wang, J. W. Reeves, T. K. Kim, Y. Kim, J. A. Guo, N. A. Lester, N. Schurman, , W. L. Hwang

This study uses single-cell spatial transcriptomics and optimal transport analysis to reveal therapy-induced changes in pancreatic cancer microenvironment interactions.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Precise DNA Cloning via PAMless CRISPR-SpRYgests

K. A. Christie, J. A. Guo, R. A. Silverstein, R. M. Doll, M. Mabuchi, H. E. Stutzman, L. Ma, G. B. Robb, B. P. Kleinstiver

This paper introduces SpRYgests, a CRISPR-based DNA cloning method that enables precise cleavage at any sequence, improving cloning workflows and reducing costs compared to restriction enzymes.

bioRxiv · Jan 11, 2022 · PreprintBiochemistry