Author

J. A. Kaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Finkbeiner· 3 shared D. Jimenez-Morales· 2 shared K. A. Fontaine· 2 shared K. E. Leon· 2 shared M. Dunlap· 2 shared M. M. Khalid· 2 shared M. Ott· 2 shared N. J. Krogan· 2 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

S. Finkbeiner

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RMeDPower2 for Biology: guiding the design, experimental structure and analyses of experiments generating repeated measures datasets

M.-G. Shin, N. Amirani, S. Lam, N. Al Bistami, K. Raja, E. Vertudes, J. A. Kaye, R. Thomas, S. Finkbeiner

RMeDPower2 helps researchers design and analyze repeated measures experiments by providing statistical tools based on GLMMs to improve reproducibility and power.

bioRxiv · Jul 18, 2022 · PreprintCell Biology

Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

K. E. Leon, R. E. Flynn, M. M. Khalid, K. A. Fontaine, T. Nguyen, R. Kumar, C. R. Simoneau, S. Tomar, D. Jimenez-Morales, M. Dunlap, J. A. Kaye, P. S. Shah, S. Finkbeiner, N. J. Krogan, C. Bertozzi, , M. Ott

This study shows ZIKV infection disrupts UPF1 function, leading to nuclear mRNA accumulation and impaired neural progenitor cell function.

bioRxiv · Dec 3, 2020 · PreprintMicrobiology

The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein

K. A. Fontaine, K. E. Leon, M. M. Khalid, S. Tomar, D. Jimenez-Morales, M. Dunlap, J. A. Kaye, P. S. Shah, S. Finkbeiner, N. J. Krogan, M. Ott

This study shows that ZIKV infection disrupts the NMD pathway by interacting with UPF1 via its capsid protein, enhancing viral infection and contributing to neuropathology.

bioRxiv · Oct 4, 2018Microbiology