Author

J. A. Tadross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. Harrison· 2 shared S. O'Rahilly· 2 shared A. A. Voors· 1 shared A. Al-Hadithi· 1 shared A. Alvarez-Guaita· 1 shared A. E. Adriaenssens· 1 shared A. Haider· 1 shared A. P. Coll· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPathology

J. Harrison

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Author profile →

3 papers

Recent·Most cited

GDF15 antagonism limits severe heart failure and prevents cardiac cachexia in mice

M. Takaoka, J. A. Tadross, A. Al-Hadithi, R. Villena-Gutierrez, J. Tromp, S. Absar, M. Au, J. Harrison, A. P. Coll, S. J. Marciniak, D. Rimmington, E. Oliver, B. Ibanez, A. A. Voors, S. O'Rahilly, , J. C. Goodall

This study shows that blocking GDF15 reduces severe heart failure and cardiac cachexia in mice by preventing weight loss and slowing disease progression.

bioRxiv · Sep 6, 2022Pathology

Endogenous GDF15 and FGF21 additively alleviate hepatic steatosis and insulin resistance in obese mice.

S. Patel, A. Haider, A. Alvarez-Guaita, G. Bidault, J. S. El-Sayed Moustafa, E. Guiu-Jurado, J. A. Tadross, J. Warner, J. Harrison, S. Virtue, F. Scurria, I. Zvetkova, M. Blüher, K. S. Small, S. O'Rahilly, D. B. Savage

This study shows that GDF15 and FGF21, secreted by the liver in obese mice, reduce hepatic steatosis and insulin resistance when both are active.

bioRxiv · Jun 8, 2022 · PreprintPhysiology

Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice

J. E. Lewis, O. R. Woodward, D. Nuzzaci, C. A. Smith, A. E. Adriaenssens, L. Billing, C. Brighton, B. U. Phillips, J. A. Tadross, S. J. Kinston, E. Ciabatti, B. Gottgens, M. Tripodi, D. Hornigold, D. Baker, , F. Reimann

This study identifies Rxfp4-expressing hypothalamic neurons as regulators of food intake and preference in mice through genetic and pharmacological manipulations.

bioRxiv · Jun 26, 2021Physiology