Author

N. Destainville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Chavent· 2 shared A. Grottesi· 1 shared A. Milon· 1 shared A.-L. Lanz· 1 shared C. Astarie-Dequeker· 1 shared C. Guilhot· 1 shared C. M. Brown· 1 shared D. Cipria· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

M. Chavent

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

From Molecular Dynamics to Supramolecular Organization: The Role of PIM Lipids in the Originality of the Mycobacterial Plasma Membrane

C. M. Brown, R. A. Corey, Y. Gao, Y. K. Choi, M. Gilleron, N. Destainville, E. Fullam, W. Im, P. J. Stansfeld, M. Chavent

This paper uses molecular dynamics simulations to study the role of PIM lipids in the structure and organization of the Mycobacterial plasma membrane and validates findings with drug testing.

bioRxiv · Jun 29, 2022Biophysics

A role of Lck annular lipids in the steady upkeep of active Lck in T cells

N. Porciello, D. Cipria, G. Masi, A.-L. Lanz, E. Milanetti, A. Grottesi, D. Howie, S. P. Cobbold, L. Schermelleh, M. D'Abramo, H.-T. He, N. Destainville, O. Acuto, K. Nika

The paper investigates how annular lipids affect Lck kinase activity in T cells by examining the balance between autophosphorylation and dephosphorylation by CD45.

bioRxiv · Mar 18, 2022 · PreprintCell Biology

The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

J. Augenstreich, E. Haanappel, G. Ferre, G. Czaplicki, F. Jolibois, N. Destainville, C. Guilhot, A. Milon, C. Astarie-Dequeker, M. Chavent

This study identifies the conical shape of DIM lipids as a key factor in promoting Mycobacterium tuberculosis infection of macrophages through phagocytosis.

bioRxiv · Jun 3, 2019Biophysics