Author

J. B. Felix

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. Cox· 3 shared K. H. Kim· 3 shared P. M. Masschelin· 3 shared P. Saha· 3 shared S. M. Hartig· 3 shared C. Coarfa· 2 shared D. A. Bader· 2 shared H. Wu· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

A. R. Cox

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Author profile →

3 papers

Recent·Most cited

Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability

P. M. Masschelin, P. Saha, S. A. Ochsner, A. R. Cox, K. H. Kim, J. B. Felix, R. Sharp, X. Li, L. Tan, J. H. Park, L. Wang, V. Putluri, P. L. Lorenzi, A. M. Nuotio-Antar, Z. Sun, , S. M. Hartig

This study shows that vitamin B2 deficiency impairs PPAR regulation of fasting glucose, and PPAR agonists can rescue this defect.

bioRxiv · Oct 16, 2022Physiology

Accumulation of auranofin in white adipose tissues lowers leptin levels and exerts anti-diabetic effects

A. R. Cox, P. M. Masschelin, P. Saha, J. B. Felix, R. Sharp, Z. Lian, Y. Xia, N. Chernis, D. A. Bader, K. H. Kim, X. Li, J. Yoshino, X. Li, Z. Sun, H. Wu, , S. M. Hartig

The paper identifies auranofin as a drug that lowers leptin levels in white adipose tissue and improves insulin sensitivity in obese mice, with anti-diabetic effects.

bioRxiv · Sep 11, 2021 · PreprintPhysiology

STAT1 dissociates adipose tissue inflammation from insulin sensitivity in obesity

A. R. Cox, N. Chernis, D. A. Bader, P. Saha, P. M. Masschelin, J. B. Felix, Z. Lian, V. Putluri, K. Rajapakshe, K. H. Kim, D. T. Villareal, R. Armamento-Villareal, H. Wu, C. Coarfa, N. Putluri, S. M. Hartig

The paper investigates how STAT1 activity in adipocytes affects insulin sensitivity in obesity, finding that STAT1 deletion improves mitochondrial function but does not resolve insulin resistance.

bioRxiv · Apr 10, 2020Immunology