Author

J. R. Webb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

B. J. Currie· 4 shared A. S. Amiss· 2 shared D. J. Craik· 2 shared D. S. Sarovich· 2 shared E. P. Price· 2 shared M. Mayo· 2 shared N. Lawrence· 2 shared R. W. Baird· 2 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

B. J. Currie

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Author profile →

4 papers

Recent·Most cited

Modified defence peptides from horseshoe crab target and kill bacteria inside host cells

A. S. Amiss, J. B. von Pein, J. R. Webb, N. D. Condon, P. J. Harvey, M.-D. Phan, M. A. Schembri, B. J. Currie, M. J. Sweet, D. J. Craik, R. Kapetanovic, S. T. Henriques, N. Lawrence

This study identifies modified antimicrobial peptides from horseshoe crabs that effectively kill bacteria, including UPEC, both extracellularly and intracellularly, with reduced toxicity to mammalian cells.

bioRxiv · Jun 27, 2021Microbiology

Drug susceptibility profiling of Australian Burkholderia species as models for developing melioidosis therapeutics

A. S. Amiss, J. R. Webb, M. Mayo, B. J. Currie, D. J. Craik, S. Troeira Henriques, N. Lawrence

The paper profiles drug susceptibility of Australian Burkholderia species to identify models for developing melioidosis therapeutics, finding high similarity in susceptibility profiles between B. pseudomallei and less pathogenic species.

The American Journal of Tropical Medicine and Hygiene · Nov 4, 2020Peer-reviewedMicrobiology

Development and validation of a triplex qPCR assay to detect efflux pump-mediated antibiotic resistance in Burkholderia pseudomallei

J. R. Webb, E. P. Price, N. Somprasong, H. P. Schweizer, R. W. Baird, B. J. Currie, D. S. Sarovich

The paper develops and validates a triplex qPCR assay to detect efflux pump upregulation in Burkholderia pseudomallei, correlating with antibiotic resistance.

bioRxiv · Apr 17, 2018Microbiology

Raising the stakes: Loss of efflux-pump regulation decreases meropenem susceptibility in Burkholderia pseudomallei

D. S. Sarovich, J. R. Webb, M. C. Pitman, L. T. Viberg, M. Mayo, R. W. Baird, J. M. Robson, B. J. Currie, E. P. Price

This study identifies mutations in RND efflux pump regulators in B. pseudomallei isolates that lead to decreased meropenem susceptibility and are associated with fatal melioidosis outcomes.

bioRxiv · Oct 20, 2017Microbiology