Author

J. Bargonetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Polotskaia· 1 shared B. Awuah· 1 shared B. Stonaker· 1 shared E. B. Osei-Bonsu· 1 shared E. Cheng· 1 shared E. K. Adjei· 1 shared F. P. M. Rowdo· 1 shared F. S. Aitpillah· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Polotskaia

Author profile →

2 papers

Recent·Most cited

A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN

V. Ellison, A. Polotskaia, P. Leybengrub, W. Qiu, R. Lee, R. C. Hendrickson, W. Hu, J. Bargonetti

This study identifies a cancer persistent DNA repair circuit involving mtp53, MDM2, and MDMX that recruits 53BP1 and MDC1 to chromatin, enhancing cell survival.

bioRxiv · Jan 20, 2024Cancer Biology

Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment

F. P. M. Rowdo, G. Xiao, G. F. Khramtsova, J. Nguyen, O. Olopade, R. Martini, B. Stonaker, R. Boateng, J. K. Oppong, E. K. Adjei, B. Awuah, I. Kyei, F. S. Aitpillah, M. O. Adinku, K. Ankomah, , J. Bargonetti

This study shows that tumor organoids with mutant p53 are more sensitive to the combination of PARP inhibitor and temozolomide than those with wild-type p53.

bioRxiv · Jun 22, 2023Cancer Biology