Author

J. Brunzelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

M. Rosas-Lemus· 2 shared A. R. Hauser· 1 shared E. A. Ozer· 1 shared G. A. Minasov· 1 shared G. MinasoviD· 1 shared K. E. R. Bachta· 1 shared K. J. F. Satchell· 1 shared K. J. Satchell· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

M. Rosas-Lemus

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Functional and Structural Characterization of OXA-935, a Novel OXA-10-family β-lactamase from Pseudomonas aeruginosa

N. B. Pincus, M. Rosas-Lemus, S. W. Gatesy, L. A. Shuvalova, J. Brunzelle, G. A. Minasov, K. J. F. Satchell, M. Lebrun-Corbin, E. A. Ozer, A. R. Hauser, K. E. R. Bachta

This study identifies and characterizes OXA-935, a novel OXA-10-family β-lactamase from Pseudomonas aeruginosa, showing it confers ceftazidime resistance through specific amino acid substitutions.

bioRxiv · Sep 20, 2021Microbiology

Structure of SARS-CoV-2 2'-O-methyltransferase heterodimer with RNA Cap analog and sulfates bound reveals new strategies for structure-based inhibitor design

M. Rosas-Lemus, G. Minasov, L. Shuvalova, N. Inniss, O. Kiryukhina, J. Brunzelle, K. J. Satchell

The paper determines the structure of SARS-CoV-2 nsp16/nsp10 2'-O-methyltransferase complex with various ligands, identifying potential sites for antiviral inhibitor design.

Science Signaling · Sep 29, 2020Peer-reviewedMicrobiology