Author

M. Rosas-Lemus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

G. MinasoviD· 3 shared J. Brunzelle· 2 shared K. J. F. Satchell· 2 shared K. J. Satchell· 2 shared L. ShuvalovaiD· 2 shared A. D. Mesecar· 1 shared A. Herrera· 1 shared A. R. Hauser· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

G. MinasovORCID

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Author profile →

4 papers

Recent·Most cited

Vibrio MARTX toxin processing and degradation of cellular Rab GTPases by the cytotoxic effector Makes Caterpillars Floppy

A. Herrera, M. M. Packer, M. Rosas-Lemus, G. Minasov, J. H. Brumell, K. J. F. Satchell

This study identifies MCF, a Vibrio effector that cleaves and degrades Rab GTPases, disrupting organelle function and promoting cell death during infection.

bioRxiv · Apr 19, 2023 · PreprintMicrobiology

Functional and Structural Characterization of OXA-935, a Novel OXA-10-family β-lactamase from Pseudomonas aeruginosa

N. B. Pincus, M. Rosas-Lemus, S. W. Gatesy, L. A. Shuvalova, J. Brunzelle, G. A. Minasov, K. J. F. Satchell, M. Lebrun-Corbin, E. A. Ozer, A. R. Hauser, K. E. R. Bachta

This study identifies and characterizes OXA-935, a novel OXA-10-family β-lactamase from Pseudomonas aeruginosa, showing it confers ceftazidime resistance through specific amino acid substitutions.

bioRxiv · Sep 20, 2021Microbiology

Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'-O-methyl transfer by SARS-CoV-2 nsp16

G. Minasov, M. Rosas-Lemus, L. Shuvalova, N. L. Inniss, J. S. Brunzelle, C. M. Daczkowski, P. Hoover, A. D. Mesecar, K. J. Satchell

Science Signaling · Jun 29, 2021Peer-reviewedMicrobiology

Structure of SARS-CoV-2 2'-O-methyltransferase heterodimer with RNA Cap analog and sulfates bound reveals new strategies for structure-based inhibitor design

M. Rosas-Lemus, G. Minasov, L. Shuvalova, N. Inniss, O. Kiryukhina, J. Brunzelle, K. J. Satchell

The paper determines the structure of SARS-CoV-2 nsp16/nsp10 2'-O-methyltransferase complex with various ligands, identifying potential sites for antiviral inhibitor design.

Science Signaling · Sep 29, 2020Peer-reviewedMicrobiology