Author

J. C. Lo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Rubio-Navarro· 2 shared N. Gomez-Banoy· 2 shared T. E. McGraw· 2 shared A. Galante· 1 shared A. Garcia-Ocana· 1 shared A. Gilani· 1 shared A. K. Li· 1 shared A. Li· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersPhysiology

A. Rubio-Navarro

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

M. Matsui, L. E. Lynch, I. Distefano, A. Galante, N. Gomez-Banoy, H.-G. Wang, A. R. Gade, D. S. Sinden, E. Q. Wei, A. S. Barnett, K. Johnson, A. Rubio-Navarro, A. K. Li, S. O. Marx, T. E. McGraw, , G. S. Pitt

This study identifies multiple beta cell-independent mechanisms causing hypoglycemia in Timothy syndrome using a novel mouse model.

bioRxiv · Jun 16, 2023Physiology

Alternative Complement Pathway Regulates Thermogenic Fat Function via Adipsin and Adipocyte-derived C3aR1 in a Sex-dependent Fashion

L. Ma, A. Gilani, A. Rubio-Navarro, E. Cortada, A. Li, S. M. Reilly, L. Tang, J. C. Lo

This study shows that the alternative complement pathway, via Adipsin and C3aR1, regulates adipose thermogenesis with sex-dependent effects, impacting energy expenditure and metabolic health.

bioRxiv · Dec 30, 2022 · PreprintCell Biology

Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant.

L. Yammine, B. Picatoste, N. Abdullah, R. Leahey, N. Gomez-Banoy, C. Rosselot, J. Wen, M. D. Goncalves, J. C. Lo, A. Garcia-Ocana, T. E. McGraw

This study investigates the impact of a GIPR variant on glucose homeostasis using a mouse model, finding altered intracellular trafficking and increased GIP sensitivity.

bioRxiv · May 12, 2020Physiology