Author

J. Cleveland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. P. Gomes· 1 shared D. Ilter· 1 shared D. Raizada· 1 shared E. A. Welsh· 1 shared F. Lazure· 1 shared G. D. Grass· 1 shared H. Enderling· 1 shared H. Kashfi· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. P. Gomes

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity

J. Tejero, R. Hesterberg, S. Drapela, D. Ilter, D. Raizada, F. Lazure, H. Kashfi, M. Liu, J. Fernandez-Garcia, S.-M. Fendt, J. Asara, J. Cleveland, A. P. Gomes

This study shows that methylmalonic acid impairs CD8+ T cell function and promotes tumor growth by inducing metabolic dysfunction and exhaustion.

bioRxiv · Mar 3, 2024Immunology

Harnessing tumor immune ecosystem dynamics to personalize radiotherapy

G. D. Grass, J. C. Lopez Alfonso, E. A. Welsh, K. Ahmed, J. Teer, L. B. Harrison, J. Cleveland, J. Mule, S. Eschrich, H. Enderling, J. Torres Roca

This study uses a computational model to analyze tumor immune ecosystem dynamics and predict how radiotherapy affects immune responses in lung cancer patients.

bioRxiv · Feb 11, 2020 · PreprintCancer Biology