Author

J. D. Langer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

J. Meier-Credo· 2 shared M. M. Nowaczyk· 2 shared A. A. Wegener· 1 shared A. Chan· 1 shared A. Krieger-Liszkay· 1 shared B. D. Engel· 1 shared B. J. Murphy· 1 shared D. J. Mills· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPlant Biology

J. Meier-Credo

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Author profile →

4 papers

Recent·Most cited

Engineering CRBN for rapid identification of next generation binders

H. J. Bailey, J. Eisert, J. Vollrath, E.-M. Leibrock, I. Kondratov, T. Matviyuk, N. Tolmachova, J. D. Langer, A. A. Wegener, F. J. Sorrell, I. Dikic

This paper introduces a new CRBN construct for efficient binder discovery, showing it outperforms existing constructs in binding and production, and applies it to identify potent CRBN binders from a large compound library.

bioRxiv · Jan 18, 2024 · PreprintBiophysics

Isolation of a novel heterodimeric PSII complex via strep-tagged PsbO

J. Lambertz, J. Meier-Credo, S. Kucher, E. Bordignon, J. D. Langer, M. M. Nowaczyk

The paper isolates a novel heterodimeric PSII complex from a cyanobacterium by fusing PsbO with a strep-tag, revealing its lower oxygen-evolving activity and manganese content compared to mature PSII.

bioRxiv · Jun 15, 2022Plant Biology

How to build a water-splitting machine: structural insights into photosystem II assembly

J. Zabret, S. Bohn, S. K. Schuller, O. Arnolds, M. Möller, J. Meier-Credo, P. Liauw, A. Chan, E. Tajkhorshid, J. D. Langer, R. Stoll, A. Krieger-Liszkay, B. D. Engel, T. Rudack, J. M. Schuller, M. M. Nowaczyk

The paper solves the structure of a PSII assembly intermediate using cryo-EM, revealing how assembly factors protect PSII during biogenesis and prepare it for water splitting.

bioRxiv · Sep 14, 2020 · PreprintPlant Biology

Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling

B. J. Murphy, N. Klusch, J. D. Langer, D. J. Mills, O. Yildiz, W. Kühlbrandt

This paper determines the cryo-EM structure of mitochondrial ATP synthase, revealing rotary substates and mechanisms of F1-Fo coupling through atomic-level analysis.

bioRxiv · Feb 6, 2019Biochemistry