Author

J. Deguine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

G. M. Barton· 2 shared A. A. Ananthakrishnan· 1 shared A. Hudak· 1 shared A. Lefkovith· 1 shared A. Regev· 1 shared A. T. Jess· 1 shared A. W. Roberts· 1 shared B. Eraslan· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

G. M. Barton

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Author profile →

3 papers

Recent·Most cited

Remodeling of human colon plasma cell repertoire in ulcerative colitis

J. F. Scheid, B. Eraslan, A. Hudak, E. Brown, D. Sergio, T. M. Delorey, D. Phillips, A. Lefkovith, A. T. Jess, L. W. Duck, C. O. Elson, H. Vlamakis, J. Deguine, A. A. Ananthakrishnan, D. B. Graham, , R. J. Xavier

This study characterizes the remodeling of the human colon plasma cell repertoire in ulcerative colitis, showing clonal expansion, isotype skewing, and altered gene expression associated with inflammation.

bioRxiv · Feb 14, 2022 · PreprintImmunology

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

C. M. Walsh, R. Z. Hill, J. Schwendinger-Schreck, J. Deguine, E. C. Brock, N. Kucirek, Z. Rifi, J. Wei, K. Gronert, R. B. Brem, G. M. Barton, D. M. Bautista

This study identifies neutrophils as key initiators of itch in atopic dermatitis and shows that CXCR3 antagonism reduces chronic itch.

bioRxiv · Sep 24, 2019Immunology

Resident Macrophages are Locally Programmed for Silent Clearance of Apoptotic Cells

A. W. Roberts, B. L. Lee, J. Deguine, S. John, M. Shlomchik, G. M. Barton

The paper identifies macrophages that silently clear apoptotic cells by expressing AC receptors and limiting nucleic acid responses, showing that tissue cues program this behavior.

bioRxiv · Jun 24, 2017Immunology