J. Du

This study identifies AGTR1 as an overexpressed target in neuroendocrine neoplasms, showing its role in secretion and potential for imaging and therapy.

This study demonstrates that transient expression of Runx1 and Hoxa9 in pluripotent stem cells generates functional T cells capable of immune surveillance and tumor eradication.

This study shows mast cells contribute to fibrosis and effector cell recruitment in dermal chronic GVHD, suggesting they are potential therapeutic targets.

This study characterizes the colonization dynamics of Rhodopseudomonas palustris GJ-22 on tobacco phyllosphere and shows it induces plant resistance to Tobacco mosaic virus.

This study identifies NADP+ and NADPH as substrates of the circadian protein Nocturnin, showing its enzymatic activity in converting these metabolites and revealing structural insights into its mechanism.

The paper presents the crystal structure of the human Nocturnin catalytic domain and identifies structural differences from related deadenylases.

This study isolates and characterizes Bacillus amyloliquefaciens subsp. plantarum XH-9, showing it promotes plant growth and suppresses Fusarium oxysporum in wheat.

The paper presents the structure of the human TRPC3 channel in a lipid-occupied closed state, revealing its unique architecture and lipid-binding sites.

The paper identifies three classes of response elements in the human genome for PRC2 and MLL1/2-TrxG complexes, revealing their distinct DNA sequence features and regulatory roles.

The paper presents a model of retinal metabolism showing glucose is converted to lactate by photoreceptors and used by retinal pigment epithelium and Muller glial cells, with implications for retinal disease and therapy.