Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
23 papers
Recent·Most cited
C. Xia, D. Colognori, X. Jiang, K. Xu, J. A. Doudna
This paper introduces smLiveFISH, a method for single-molecule live-cell imaging of endogenous RNA using CRISPR-Csm, and identifies two distinct mRNA localization mechanisms.
bioRxiv · Jul 14, 2024Biophysics
C. Xia, H. Xu, L. Fang, J. Chen, W. Yuan, D. Fu, X. Wang, B. He, L. Xiao, C. Wu, P. Tong, D. Chen, P. Wang, H. Jin
This study shows that β-catenin inhibition disrupts osteogenic/adipogenic differentiation in bone marrow mesenchymal cells, contributing to glucocorticoid-induced osteonecrosis of the femoral head.
bioRxiv · Oct 4, 2023Pathology
C. Xia, C. Xia, L. Huang, N. Zhao, H. Li, X. Zhang, A. Qiu, W. Tang, M. Wang, X. Chen, B. Liu, H. Zhang, L. Gao, W. Chen, T. Liu
This study uses population genomic analyses to identify genomic regions under selection and demographic history of the wheat rust pathogen Pst, revealing adaptation mechanisms and population size changes linked to wheat domestication and agriculture.
bioRxiv · Aug 29, 2023Microbiology
X. Dong, X. Zhang, Z. Yin, J. Li, C. Xia, W. Pan, Y. Zhao, M. Jing, J. Liu, G. Ai, D. Dou
The paper identifies paired NLRs in Solanaceae species and shows their coordinated role in modulating NRC3-mediated ETI to enhance age-dependent immunity.
bioRxiv · Dec 20, 2022 · PreprintPlant Biology
L. Liu, P. Wang, S.-Q. Xie, W.-J. Pu, J. Xu, c. Xia
The study investigates how ICOS/ICOSL signaling regulates macrophage polarization and IL-33's role in liver fibrosis progression in mice with schistosomiasis.
bioRxiv · Sep 5, 2022 · PreprintImmunology
h. huang, Z. Li, X. Yang, Z. Ding, L. Peng, Q. Song, F. Cui, D. Zhang, C. Xia, K. Li, H. Yin, S. Li
This study reports cryo-EM structures of human enteropeptidase in multiple states, revealing its activation mechanism and substrate recognition process.
bioRxiv · Mar 7, 2022Cell Biology
D. Huang, J. Li, F. Hu, Q. Weng, T. Wang, H. Peng, B. Wu, C. Xia, H. Wu, J. Xiong, J. Lin, Y. Lin, Y. Wang, Q. Zhang, X. Liu, , J. Wang
This study develops an organoid-based method to generate large quantities of NK cells from human pluripotent stem cells without feeder cells, achieving efficient and scalable iNK cell production.
bioRxiv · Dec 3, 2021Immunology
F. Hu, D. Huang, Q. Zhao, Q. Weng, Q. Zhang, K. Wang, L. Liu, C. Xia, T. Wang, J. Xiong, X. Liu, Y. Guan, Y. Geng, F. Dong, H. Cheng, , J. Wang
This study shows that Hoxb5 can convert multipotent blood progenitors into hematopoietic stem cell-like cells with long-term repopulating ability.
bioRxiv · Oct 25, 2021 · PreprintCell Biology
Q. Zhang, B. Wu, Q. Weng, F. Hu, Y. Lin, C. Xia, H. Peng, Y. Wang, X. Liu, L. Liu, J. Xiong, Y. Geng, Y. Zhao, M. Zhang, J. Du, J. Wang
This study regenerates functional B lymphopoiesis from pluripotent stem cells (PSCs) using Runx1, Hoxa9, and Lhx2, producing antigen-specific antibodies and immune memory in B-cell deficient animals.
bioRxiv · Jul 30, 2021 · PreprintImmunology
H. Tao, H. Miao, L. Chen, M. Wang, C. Xia, W. Zeng, Y. Li, S. Zhang, C. Li, Q. Wang
WRKY33 regulates indole glucosinolate biosynthesis and hydrolysis, enhancing resistance to Alternaria brassicicola in Arabidopsis and Brassica crops.
bioRxiv · Apr 22, 2021 · PreprintPlant Biology
M. Li, R. Zhao, J. Chen, W. Tian, C. Xia, X. Liu, Y. Li, Y. Yan, S. Li, H. Sun, T. Shen, W. Ren, L. Sun
This paper describes the development of a modified Atezolizumab (Maxatezo) with improved anti-tumor efficacy and reduced anti-drug antibody formation in vivo.
Scientific Reports · Mar 11, 2021Peer-reviewedBioengineering
B. Sun, Y. Wang, Z. Wang, S. Lu, C. Xia
The paper identifies dominant cytotoxic T lymphocyte epitopes of Marek's disease virus, confirms their immunoprotective effects, and highlights key factors for effective antitumor immunity.
bioRxiv · Jan 25, 2021 · PreprintImmunology
C. xia, Z. Fu, B. Lou, A.-W. Mohsen, J. Vockley, J. J. kim
This study investigates the molecular mechanism of ACAD9 in mitochondrial respiratory complex 1 assembly, revealing its dual role as a chaperone and its structural interactions with ECSIT and NDUFAF1.
bioRxiv · Jan 7, 2021 · PreprintBiochemistry
Y. Sun, L. Ma, S. Li, Y. Wang, R. Xiao, J. Yang, C. Xia
This study determines the crystal structure of pDLA-88*001:01 and identifies its peptide-binding motif, revealing structural differences between two categories of DLA-88 alleles in dogs and their implications for antiviral immunity.
bioRxiv · Jan 4, 2021 · PreprintImmunology
T. Wang, C. Xia, Q. Weng, K. Wang, Y. Dong, S. Hao, F. Dong, X. Liu, L. Liu, Y. Geng, Y. Guan, J. Du, T. Cheng, H. Cheng, J. Wang
This study shows that deleting Nupr1 in HSCs activates quiescence, enhancing engraftment without affecting stemness or differentiation.
bioRxiv · Jul 16, 2020Cell Biology
R. Amraei, M. Napoleon, W. Yin, J. Berrigan, E. Suder, G. Zhao, J. Olejnik, K. Chandler, C. Xia, S. Gummuluru, E. Muhlberger, V. Chitalia, C. Costello, N. Rahimi
This study identifies CD209L/L-SIGN and CD209/DC-SIGN as alternative receptors for SARS-CoV-2, capable of mediating virus entry into human cells, particularly in tissues with low ACE2 expression.
bioRxiv · Jun 22, 2020 · PreprintCell Biology
W. Ren, H. Sun, G. F. Gao, J. Chen, S. Sun, R. Zhao, G. Gao, Y. Hu, G. Zhao, Y. Chen, X. Jin, F. Fang, J. Chen, Q. Wang, S. Gong, , L. Sun
This study shows that a recombinant SARS-CoV-2 S1-Fc fusion protein induces strong neutralizing antibodies in nonhuman primates and can be produced at scale for vaccine development.
bioRxiv · Apr 21, 2020Immunology
C. Xia, T. Wang, H. Cheng, Y. Dong, Q. Weng, G. Sun, P. Zhou, K. Wang, X. Liu, Y. Geng, S. Ma, S. Hao, L. Xu, Y. Guan, J. Du, , J. Wang
This study shows that intra-BM MSC transfusion restores the BM microenvironment, suppresses leukemia, and reprograms macrophages to reduce tumor burden.
Leukemia · Feb 24, 2020Peer-reviewedCancer Biology
W. W. Qian, C. Xia, S. Venugopalan, A. Narayanaswamy, J. Peng, D. M. Ando
This paper develops a GAN-based method to reduce batch effects in image data by transferring images between batches while preserving biological features.
bioRxiv · Feb 7, 2020Cell Biology
H. Yuan, L. Ma, L. Zhang, X. Li, C. Xia
This paper solves the crystal structure of the giant panda MHC class I complex, revealing unique features of viral peptide presentation in the bear family and providing insights for vaccine design.
bioRxiv · Jan 15, 2020Immunology
R. Guo, F. Hu, Q. Weng, C. Lv, H. Wu, L. Liu, Z. Li, Y. Zeng, Z. Bai, M. Zhang, Y. Liu, X. Liu, C. Xia, T. Wang, P. Zhou, , J. Wang
This study demonstrates that transient expression of Runx1 and Hoxa9 in pluripotent stem cells generates functional T cells capable of immune surveillance and tumor eradication.
bioRxiv · Oct 12, 2019Immunology