Author

J. Dubois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Pizzorno· 5 shared A. Traversier· 5 shared B. Lina· 5 shared B. Padey· 5 shared M. Rosa-Calatrava· 5 shared O. Terrier· 5 shared T. Julien· 5 shared C. Nicolas de Lamballerie· 3 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

A. Pizzorno

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Time-Domain Diffuse Optical Tomography for Precision Neuroscience

Y. Chekin, D. Decker, H. Dehghani, J. Dubois, R. M. Field, V. Gopalakrishnan, E. M. Koch, G. Lerner, Z. M. Aghajan, N. Miller, I. Olvera, M. J. Patel, K. L. Perdue, J. Schmidt, V. Szczepanski

This paper presents a whole-head time-domain diffuse optical tomography (TD-DOT) system, characterizes its performance, and demonstrates its ability to retrieve cortical activation maps during various tasks.

bioRxiv · Apr 30, 2024Bioengineering

A novel effective live-attenuated human metapneumovirus vaccine candidate produced in the serum-free suspension DuckCelt-T17 cell platform

C. Chupin, A. Pizzorno, A. Traversier, P. Brun, D. Ogonczyk-makowska, B. Padey, C. Milesi, V. Duliere, E. Laurent, T. Julien, M. Galloux, B. Lina, J.-F. Eleouet, K. Moreau, M.-E. Hamelin, , M. Rosa-Calatrava

This study evaluates the use of DuckCelt-T17 avian cells for producing a live-attenuated HMPV vaccine candidate, showing its efficiency and scalability.

bioRxiv · Aug 30, 2021 · PreprintImmunology

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

C. Nicolas de Lamballerie, A. Pizzorno, J. Dubois, B. Padey, T. Julien, A. Traversier, J. Carbonneau, E. Orcel, B. Lina, M.-E. Hamelin, M. Roche, J. Textoris, G. Boivin, C. Legras-Lachuer, O. Terrier, M. Rosa-Calatrava

This study identifies an HRSV-induced immune signature in pediatric nasal wash samples using transcriptome analysis.

bioRxiv · May 20, 2020Microbiology

Transcriptional profiling of immune and inflammatory responses in the context of SARS-CoV-2 fungal superinfection in a human airway epithelial model

C. Nicolas de Lamballerie, A. Pizzorno, J. Fouret, L. szpiro, B. Padey, J. Dubois, T. Julien, A. Traversier, V. Duliere, P. Brun, B. Lina, M. Rosa-Calatrava, O. Terrier

The paper compares the transcriptional responses of SARS-CoV-2 and Aspergillus superinfection in human airway epithelial models, identifying unique immune and inflammatory signatures.

bioRxiv · May 19, 2020Microbiology

Characterization and treatment of SARS-CoV-2 in nasal and bronchial human airway epithelia

A. Pizzorno, B. Padey, T. Julien, S. Trouillet-Assant, A. Traversier, E. Errazuriz-Cerda, J. Fouret, J. Dubois, A. Gaymard, X. Lescure, V. Duliere, P. Brun, S. Constant, J. Poissy, B. Lina, , M. Rosa-Calatrava

The paper characterizes SARS-CoV-2 infection in nasal and bronchial airway epithelial models and evaluates the antiviral efficacy of remdesivir and its combination with diltiazem.

bioRxiv · Mar 31, 2020Microbiology

Oncoprotein 18 is necessary for malignant cell proliferation in bladder cancer cells and serves as a G3-specific non-invasive diagnostic marker candidate in urinary RNA

M. Hanke, J. Dubois, I. Kausch, S. Petkovic, G. Sczakiel

This study shows OP18 is essential for bladder cancer cell proliferation and identifies it as a potential non-invasive diagnostic marker in urinary RNA.

bioRxiv · Feb 3, 2020Cancer Biology

Strain-dependent impact of G and SH deletions provide new insights for live-attenuated HMPV vaccine development

J. Dubois, A. Pizzorno, M.-H. Cavanagh, B. Padey, C. Nicolas de Lamballerie, O. Uyar, M.-C. Venable, J. Carbonneau, A. Traversier, T. Julien, C. Couture, B. Lina, M.-E. Hamelin, O. Terrier, M. Rosa-Calatrava, G. Boivin

This study evaluates strain-dependent effects of G and SH deletions in HMPV to inform live-attenuated vaccine development, finding that SH-deleted A1/C-85473 virus is attenuated and protective in mice.

bioRxiv · Sep 25, 2019Microbiology

Molecular mechanism of the chitinolytic monocopper peroxygenase reaction

B. Bissaro, B. Streit, I. Isaksen, V. G. H. Eijsink, G. T. Beckham, J. DuBois, A. K. Rohr

This paper elucidates the H2O2-mediated reaction mechanism of chitinolytic LPMOs using experimental and computational approaches, revealing key kinetic and structural insights.

bioRxiv · Feb 5, 2019Biochemistry