Author

J. E. Sealey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:E. coli· 2 Assay:whole-genome sequencing· 2 Organism:chicken / avian· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. B. Avison· 4 shared K. K. Reyher· 2 shared V. C. Gould· 2 shared A. Hammond· 1 shared A. M. Daum· 1 shared A. Turner· 1 shared B. Astley· 1 shared C. Reding· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersMicrobiology

M. B. Avison

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Author profile →

4 papers

Recent·Most cited

Similarities Between Antibiotic-Resistant Escherichia coli from Raw Meat, Commercial Raw Dog Food and Those Causing Extraintestinal Human Infections: A Contemporaneous Geographically Focussed Genomic Epidemiology Study

J. E. Sealey, B. Astley, K. L. Sealey, A. M. Daum, D. Kiziltan, L. Wright, P. Williams, M. B. Avison

This study compares antibiotic-resistant E. coli from raw meat, commercial raw dog food, and human infections, finding close genetic links between them.

Clinical Microbiology and Infection · Jul 1, 2026Peer-reviewedMicrobiology

Improving Nitrofurantoin Resistance Prediction in Escherichia coli from Whole Genome Sequence by Integrating NfsA/B Enzyme Assays

P. Dulayangkul, J. E. Sealey, W. W. Lee, C. Reding, K. J. Heesom, N. Satapoomin, P. B. Williams, M. B. Avison

The paper identifies specific amino acid substitutions in NfsA and NfsB that reduce enzyme activity and cause nitrofurantoin resistance in E. coli, but finds that WGS alone cannot reliably predict resistance due to functional silent mutations and downregulated gene expression.

bioRxiv · Jan 25, 2024 · PreprintMicrobiology

Similarities and differences in molecular epidemiology of third-generation cephalosporin-resistant Escherichia coli carried by dogs living in urban and nearby rural settings and associated behavioural risk factors

J. E. Sealey, A. Hammond, O. Mounsey, V. C. Gould, K. K. Reyher, M. B. Avison

This study compares third-generation cephalosporin-resistant E. coli in dogs from urban and rural areas, identifying risk factors and zoonotic transmission links with humans and cattle.

bioRxiv · Apr 23, 2022 · PreprintMicrobiology

Factors Influencing the Detection of Antibacterial Resistant Escherichia coli in Faecal Samples from Individual Cattle

A. Turner, H. Schubert, E. F. Puddy, J. E. Sealey, V. C. Gould, T. A. Cogan, M. B. Avison, K. K. Reyher

This study examines factors affecting the detection of antibiotic-resistant E. coli in cattle faecal samples, finding that sampling methods and storage duration are more influential than on-farm antibiotic use.

bioRxiv · Nov 7, 2021Microbiology