O. Mounsey

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

The paper shows that gene cassettes in an integron, amplified by IS26, confer resistance to amikacin and piperacillin/tazobactam, often leaving meropenem as the last-resort antibiotic.

Genomic epidemiology of third-generation cephalosporin-resistant Escherichia coli from Argentinian pig and dairy farms reveals animal-specific patterns of co-resistance and resistance mechanisms

This study identifies animal-specific patterns of third-generation cephalosporin resistance in E. coli from Argentinian pig and dairy farms, revealing differences in resistance mechanisms and co-resistance patterns.

Similarities and differences in molecular epidemiology of third-generation cephalosporin-resistant Escherichia coli carried by dogs living in urban and nearby rural settings and associated behavioural risk factors

This study compares third-generation cephalosporin-resistant E. coli in dogs from urban and rural areas, identifying risk factors and zoonotic transmission links with humans and cattle.

Limited Phylogenetic Overlap Between Fluoroquinolone-Resistant Escherichia coli Isolated on Dairy Farms and those Causing Bacteriuria in Humans Living in the Same Geographical Region

The paper investigates the link between fluoroquinolone-resistant E. coli on dairy farms and human bacteriuria in the same region, finding limited phylogenetic overlap and identifying farm use patterns as risk factors.

Evidence that faecal carriage of resistant Escherichia coli by 16-week-old dogs in the United Kingdom is associated with raw feeding

This study links raw feeding in 16-week-old UK dogs to carriage of antibiotic-resistant E. coli, with some strains shared with human infections.

Reduced antibacterial drug resistance and blaCTX-M β-lactamase gene carriage in cattle-associated Escherichia coli at low temperatures, at sites dominated by older animals and on pastureland: implications for surveillance.

This study identifies factors influencing antibacterial resistance in E. coli on dairy farms, showing that lower temperatures, older animal environments, and pastureland reduce resistance and blaCTX-M gene carriage.

Trade-Offs Between Antibacterial Resistance and Fitness Cost in the Production of Metallo-β-Lactamase by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting.

The paper shows how meropenem resistance via NDM-1 in Enterobacteriales involves trade-offs between resistance and fitness, leading to sporadic resistance emergence in clinical settings.

Molecular epidemiology of Escherichia coli producing CTX-M and plasmid AmpC-type β-lactamases from dairy farms identifies a dominant plasmid encoding CTX-M-32 but no evidence for transmission to humans in the same geographical region

The paper analyzes 3GC-R E. coli from dairy farms and human urinary samples in the same region, finding a dominant plasmid but no evidence of human transmission.

Characterisation of AmpC Hyper-Producing Escherichia coli from Humans and Dairy Farms Collected in Parallel in the Same Geographical Region

This study characterizes AmpC hyper-producing E. coli from dairy farms and humans, identifies risk factors, and finds no evidence of zoonotic transmission.