Staphylococcus aureus wall teichoic acid is a pathogen-associated molecular pattern that is recognized by langerin (CD207) on skin Langerhans cells
R. van Dalen, J. S. De La Cruz Diaz, M. Rumpret, F. F. Fuchsberger, N. H. van Teijlingen, J. Hanske, C. Rademacher, T. B. H. Geijtenbeek, J. A. G. Van Strijp, C. Weidenmaier, A. Peschel, D. H. Kaplan, N. M. van Sorge
This study shows that S. aureus wall teichoic acid is recognized by langerin on human Langerhans cells, driving Th1/Th17 responses and inflammation in skin diseases.
bioRxiv · Oct 17, 2018 · PreprintMicrobiology