Author

J. Hubbell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Solanki· 4 shared E. Budina· 3 shared M. J. V. WHITE· 3 shared S. Cao· 3 shared A. T. Alpar· 2 shared L. T. Gray· 2 shared M. Nguyen· 2 shared M. Raczy· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersBioengineering

A. Solanki

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Injectable butyrate-prodrug micelles induce long-acting immune modulation and suppress autoimmune arthritis in mice

S. Cao, E. Budina, R. Wang, M. Sabados, A. Solanki, M. Nguyen, K. Hultgren, A. Dhar, J. Hubbell

This study develops butyrate-prodrug micelles that target lymphatics to induce long-term immune modulation and reduce arthritis in mice.

bioRxiv · Aug 20, 2023 · PreprintBioengineering

Engineered collagen-targeting therapeutics reverse lung and kidney fibrosis in mice

M. J. V. WHITE, M. Raczy, E. Budina, A. Solanki, Z. J. Zhang, L. T. Gray, S. Cao, A. T. Alpar, J. Hubbell

This study develops collagen-targeted therapeutics that reduce lung and kidney fibrosis in mice by improving drug delivery and efficacy.

bioRxiv · Jan 4, 2022 · PreprintBioengineering

Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity

L. R. Volpatti, R. P. Wallace, S. Cao, M. Raczy, R. Wang, L. T. Gray, A. T. Alpar, P. S. Briquez, N. Mitrousis, T. M. Marchell, M. S. Sasso, M. Nguyen, A. Mansurov, E. Budina, A. Solanki, , J. Hubbell

This study develops a subunit nanovaccine using polymersomes decorated with SARS-CoV-2 RBD, showing enhanced neutralizing antibody and T cell responses in mice.

ACS Central Science · Jul 21, 2021Peer-reviewedBioengineering

VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes

M. J. V. WHITE, P. Briquez, D. A. V. White, J. Hubbell

This paper shows that engineered growth factors with enhanced ECM binding improve wound healing in a type 1 diabetes model, with triple therapy being most effective.

bioRxiv · Jun 21, 2021Bioengineering

Myofibroblast differentiation is governed by adhesion mechanics, and inhibition of the stress sensor Talin2 reverses lung fibrosis

M. J. V. WHITE, M. Ozkan, J. E. G. Medellin, A. Solanki, J. Hubbell

The paper identifies Talin2 as a key regulator of myofibroblast differentiation and shows that its inhibition reverses fibrosis in lung and kidney models.

bioRxiv · Jun 7, 2021 · PreprintImmunology

J. Hubbell · henhao