Author

J. J. Alston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Organism:virus· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. S. Holehouse· 3 shared A. Soranno· 3 shared J. Cubuk· 2 shared J. J. Incicco· 2 shared K. B. Hall· 2 shared M. D. Stuchell-Brereton· 2 shared D. Griffith· 1 shared G. M. Ginell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

A. S. Holehouse

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins

J. J. Alston, G. M. Ginell, A. Soranno, A. S. Holehouse

The paper introduces the analytical Flory Random Coil (AFRC) model as a reference for unfolded proteins, enabling comparison of experimental and simulation data.

bioRxiv · Mar 12, 2023 · PreprintBiophysics

The disordered N-terminal tail of SARS CoV-2 Nucleocapsid protein forms a dynamic complex with RNA

J. Cubuk, J. J. Alston, J. J. Incicco, A. S. Holehouse, K. B. Hall, M. D. Stuchell-Brereton, A. Soranno

This study investigates how the disordered N-terminal tail of the SARS-CoV-2 Nucleocapsid protein enhances RNA binding affinity and modulates interactions with RNA.

bioRxiv · Feb 10, 2023Biophysics

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

J. Cubuk, J. J. Alston, J. J. Incicco, S. Singh, M. D. Stuchell-Brereton, M. D. Ward, M. I. Zimmerman, N. Vithani, D. Griffith, J. A. Wagoner, G. R. Bowman, K. B. Hall, A. Soranno, A. S. Holehouse

This study investigates the SARS-CoV-2 nucleocapsid protein's dynamics, disorder, and RNA phase separation using single-molecule spectroscopy and simulations, revealing its multivalent RNA binding properties and phase separation behavior.

bioRxiv · Jun 17, 2020Biophysics