Author

J. Jakob

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. N. R. Weber· 1 shared A. Reddy· 1 shared A. Smith· 1 shared A. Tondervik· 1 shared B. Hube· 1 shared B. Moerschbacher· 1 shared C.-L. Greve· 1 shared D. Le Roy· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. N. R. Weber

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2 papers

Recent·Most cited

Monocarboxylate transporters facilitate succinate uptake into brown adipocytes

A. Reddy, S. Winther, N. Tran, H. Xiao, J. Jakob, R. Garrity, A. Smith, E. Mills, E. Chouchani

This study identifies monocarboxylate transporters (MCTs) as facilitators of succinate uptake into brown adipocytes, showing their role in metabolic disease protection.

bioRxiv · Mar 1, 2023Cell Biology

Transkingdom mechanism of MAMP generation by chitotriosidase (CHIT1) feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

T.-H. Chang, Y. C. Gloria, M. J. Hellmann, C.-L. Greve, D. Le Roy, T. Roger, F. Bork, S. Bugl, J. Jakob, L. Kasper, B. Hube, S. Pusch, N. Gow, M. Sorlie, A. Tondervik, , A. N. R. Weber

This study identifies CHIT1 as an enzyme that converts fungal chitin into oligomers sensed by TLR2, revealing a mammalian MAMP generation system similar to plants.

bioRxiv · Feb 17, 2022Immunology