Author

A. N. R. Weber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. W. Loeffler· 3 shared F. Herster· 2 shared K. Ghoreschi· 2 shared K. Schaekel· 2 shared Z. Bittner· 2 shared A. Ducroux· 1 shared A. Tondervik· 1 shared B. Hube· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

M. W. Loeffler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transkingdom mechanism of MAMP generation by chitotriosidase (CHIT1) feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

T.-H. Chang, Y. C. Gloria, M. J. Hellmann, C.-L. Greve, D. Le Roy, T. Roger, F. Bork, S. Bugl, J. Jakob, L. Kasper, B. Hube, S. Pusch, N. Gow, M. Sorlie, A. Tondervik, , A. N. R. Weber

This study identifies CHIT1 as an enzyme that converts fungal chitin into oligomers sensed by TLR2, revealing a mammalian MAMP generation system similar to plants.

bioRxiv · Feb 17, 2022Immunology

A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913

J. Kazmierski, C. Elsner, K. Doehner, S. Xu, A. Ducroux, F. Pott, J. Jansen, C. W. Thorball, O. Zeymer, X. Zhou, R. Fedorov, J. Fellay, M. W. Loeffler, A. N. R. Weber, B. Sodeik, C. Goffinet

This study shows that the cGAS variant rs610913 maintains a baseline antiviral state, slightly altering susceptibility to viral infections without gross phenotypic differences.

bioRxiv · Aug 24, 2021 · PreprintImmunology

Neutrophil-extracellular trap-associated RNA (naRNA) and LL37 enable self-amplifying inflammation in psoriasis

F. Herster, Z. Bittner, S. Dickhoefer, D. Eisel, T. Eigenbrod, T. Knorpp, N. Schneiderhan-Marra, M. W. Loeffler, H. Kalbacher, D. Hartl, L. Freund, K. Schaekel, M. Heiser, K. Ghoreschi, A. N. R. Weber

The paper shows RNA-LL37 complexes activate neutrophils via TLR8, leading to cytokine release and NET formation, which may drive self-sustaining inflammation in psoriasis.

bioRxiv · Feb 19, 2019 · PreprintImmunology

Platelet-neutrophil aggregates promote skin pathology in psoriasis

F. Herster, Z. Bittner, M. C. Codrea, N. Archer, M. Heister, M. W. Loeffler, S. Heumos, J. Wegner, R. Businger, M. Schindler, D. Stegner, K. Schaekel, S. Grabbe, K. Ghoreschi, L. Miller, A. N. R. Weber

This study identifies platelet-neutrophil aggregates as contributors to psoriasis skin pathology and disease severity.

bioRxiv · Jan 28, 2019 · PreprintImmunology