J. Klingstrom

Altered DNA methylation pattern contributes to differential epigenetic immune signaling in the upper respiratory airway of COVID-19 patients

This study identifies altered DNA methylation patterns in the upper respiratory airway of COVID-19 patients, highlighting changes in immune-related genes and potential implications for airway health.

Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster

This study shows that a monovalent XBB.1.5-adapted BNT162b2 booster vaccine enhances binding and neutralizing antibodies against XBB.1.5 and BA.2.86 in elderly individuals with prior vaccinations.

Discovery of a novel inhibitor of macropinocytosis with antiviral activity

This study identifies virapinib, a novel inhibitor of macropinocytosis that blocks viral entry by SARS-CoV-2, Monkeypox virus, and TBEV without host cell toxicity.

SARS-CoV-2 variant-specific differences in inhibiting the effects of the PKR-activated integrated stress response

This study examines how different SARS-CoV-2 variants affect the integrated stress response by varying their activation of PKR and downstream effects.

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19

The paper maps SARS-CoV-2-specific T cell responses in individuals with asymptomatic/mild COVID-19 and finds robust memory T cell responses similar to vaccines, detectable even in antibody-seronegative individuals.

The generation of plasma cells and CD27-IgD- B cells during Hantavirus infection are associated with distinct pathological findings

This study links plasma cell and CD27-IgD- B cell generation during Hantavirus infection to distinct pathological features in HFRS.