Author

M. Haraldsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Corman· 1 shared A.-L. Gustavsson· 1 shared A.-S. Jemth· 1 shared B. Porebski· 1 shared C. B. Paulin· 1 shared C. Dirks· 1 shared D. Huhn· 1 shared E. J. Homan· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Corman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of a novel inhibitor of macropinocytosis with antiviral activity

B. Porebski, W. Christ, A. Corman, M. Haraldsson, M. Barz, L. Lidemalm, M. Haggblad, J. Illmain, S. Wright, M. Murga, J. Schlegel, E. Sezgin, G. Bhabha, V. M. Lauschke, M. Lafarga, , O. Fernandez-Capetillo

This study identifies virapinib, a novel inhibitor of macropinocytosis that blocks viral entry by SARS-CoV-2, Monkeypox virus, and TBEV without host cell toxicity.

bioRxiv · Oct 25, 2023Pharmacology & Toxicology

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

S. M. Zhang, C. B. Paulin, M. Michel, P. Marttila, M. Yagüe-Capilla, H. C. Bwanika, H. Shu, R. Papagudi Vekatram, E. Wiita, A.-S. Jemth, I. Almlöf, O. Loseva, F. Ortis, C. Dirks, T. Koolmeister, , S. G. Rudd

This paper identifies and evaluates small-molecule inhibitors of SAMHD1 through a comprehensive screening pipeline, revealing a novel mode of inhibition and potential therapeutic applications.

bioRxiv · Jan 17, 2023 · PreprintBiochemistry

Inhibition of the ubiquitin-proteasome system by a bioactivatable compound

T. A. Giovannucci, F. Salomons, M. Haraldsson, L. Elfman, M. Wickstrom, P. Young, T. Lundback, J. Eirich, M. Altun, R. Jafari, A.-L. Gustavsson, J. I. Johnson, N. Dantuma

The paper identifies CBK77, a bioactivatable compound that inhibits the ubiquitin-proteasome system by targeting NQO1, leading to cell death in cancer cells.

bioRxiv · Mar 16, 2021Cell Biology