Author

J. L. Grit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

C. J. Essenburg· 2 shared C. R. Graveel· 2 shared E. A. Tovar· 2 shared I. Beddows· 2 shared M. Arumugam· 2 shared C. R. Esquibel· 1 shared E. F. Petricoin· 1 shared E. Wolfrum· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

C. J. Essenburg

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Author profile →

2 papers

Recent·Most cited

p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs

J. L. Grit, L. E. McGee, E. A. Tovar, C. J. Essenburg, E. Wolfrum, I. Beddows, K. Williams, R. Sheridan, J. Schipper, M. Adams, M. Arumugam, T. Vander Woude, S. Gurunathan, J. M. Field, J. Wulfkuhle, , M. Steensma

This study shows p53 loss in NF1-related MPNSTs leads to MET instability, kinome reprogramming, and therapy resistance through altered signaling and lineage plasticity.

bioRxiv · Jan 18, 2023Cancer Biology

Nf1 deficiency accelerates mammary development and promotes luminal-basal plasticity

E. A. Tovar, M. Arumugam, C. J. Essenburg, P. S. Dischinger, J. L. Grit, M. Callaghan, R. T. C. Sheridan, L. Turner, C. R. Esquibel, K. Feenstra, Z. Madaj, I. Beddows, C. R. Graveel, M. R. Steensma

This study shows that Nf1 deficiency in rats accelerates mammary development and promotes luminal-basal plasticity and EMT-mediated invasion.

bioRxiv · Dec 22, 2022 · PreprintCancer Biology