Author

S. R. Nielsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Baccarini· 2 shared B. D. Brown· 2 shared L. Pia· 2 shared M. Merad· 2 shared A. Bektesevic· 1 shared A. H. Rahman· 1 shared A. Lakshmi· 1 shared A. Marks· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

A. Baccarini

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivDec 17, 2021

Targeting macrophages with CAR-T cells delays solid tumor progression and enhances anti-tumor immunity

A. R. Sanchez-Paulete, J. Mateus-Tique, G. Mollaoglu…·B. D. Brown

This study shows that CAR-T cells targeting macrophages delay tumor growth and improve survival in mouse models of solid tumors by enhancing anti-tumor immunity.

DOI 10.1158/2326-6066.cir-21-1075

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 13, 2021

Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition

M. Dhainaut, S. A. Rose, G. Akturk…·B. D. Brown

Perturb-map enables spatial CRISPR screening in tumors, identifying genes that regulate immune composition by mapping gene knockouts and their effects on the tumor microenvironment.

DOI 10.1101/2021.07.13.451021

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivDec 15, 2017

Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer

V. Quaranta, C. Rainer, S. R. Nielsen…·M. Schmid

This study shows that macrophage-derived granulin promotes resistance to immune checkpoint inhibitors in metastatic pancreatic cancer by excluding CD8+ T cells, and blocking granulin improves anti-tumor immunity.

DOI 10.1158/0008-5472.can-17-3876

mouseproteomics

𝕏 PostBluesky