J. Lourenco

The historical ecological background of West Nile virus in Portugal provides One Health opportunities into the future

This study uses ecological niche modeling to analyze historical WNV data in Portugal, identifying climate and environmental factors that influence its spread and proposing a framework for future surveillance.

Genomic tailoring of autogenous poultry vaccines to reduce Campylobacter from farm to fork

This paper develops a genomic autogenous vaccine for poultry to reduce Campylobacter, showing reduced extra-intestinal survival genes and meat surface survival in vaccinated flocks.

Tecovirimat is highly efficient on the Monkeypox virus lineage responsible for the international 2022 outbreak

This study tests tecovirimat's efficacy against the 2022 MPXV outbreak strain, showing nanomolar activity compared to cidofovir's micromolar activity.

NFAT5 induction by the tumor microenvironment enforces CD8 T cell exhaustion

This study identifies NFAT5 as a key driver of CD8 T cell exhaustion in the tumor microenvironment, showing its role in reducing tumor control and its absence improving it.

Fiber-parenchyma trade-off underlies changes in tropical forest structure and xylem architecture across a soil water gradient

The paper examines how fiber and parenchyma traits in tree xylem vary with soil water gradients, revealing a trade-off between hydraulic safety and resource acquisition.

Interactions between xylem traits linked to hydraulics during xylem development optimize growth performance in conifer seedlings

This study examines how xylem traits linked to hydraulics change during xylem development in conifer seedlings, finding that jack pine maintains hydraulic safety traits and associates tracheid expansion with growth performance.

Machine learning models exploring characteristic single-nucleotide signatures in Yellow Fever Virus

This paper uses machine learning to analyze YFV genomic data and identifies SNVs potentially linked to disease severity and PCR Ct values in human and NHP infections.

Within-host competition modulates pneumococcal antibiotic resistance in the pre-vaccination era

This study uses a stochastic model to show that within-host competition explains variation in pneumococcal antibiotic resistance frequencies in the pre-vaccination era.

Assessing trait driver theory along abiotic gradients in tropical plant communities

The paper tests trait driver theory along a steep soil water availability gradient in tropical plant communities, finding shifts in trait distributions and functional convergence consistent with environmental filtering and phenotype-environment matching.

Drivers of plant traits and forest functional composition in coastal plant communities of the Atlantic Forest

The paper identifies key environmental drivers of functional composition in coastal Atlantic Forest restinga communities, highlighting water availability and soil chemistry as critical factors.

Classification of hospital and urban wastewater resistome and microbiota over time and their relationship to the eco-exposome.

The paper analyzes the resistome, microbiota, and eco-exposome of hospital and urban wastewater over time and their mixing impact on AMR.

HBV vaccination and PMTCT as elimination tools in the presence of HIV: insights from a clinical cohort and dynamic model

This study evaluates HBV vaccination and PMTCT as tools for elimination in HIV-coinfected populations using a clinical cohort and dynamic model, showing potential for significant public health impact by 2030.