APOBEC3F is the main source of editing identified during the 2022 outbreak of human monkeypox virus
R. Suspene, K. A. Raymond, L. Boutin, S. Guillier, F. Lemoine, O. Ferraris, J.-N. Tournier, F. Iseni, E. Simon-Loriere, J.-P. Vartanian
The paper identifies APOBEC3F as the main source of hypermutation in MPXV during the 2022 outbreak, showing its role in generating G->A mutations and subsequent viral evolution.
bioRxiv · Jan 6, 2023 · PreprintMicrobiology