Author

A. Wiegand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. W. Mellors· 3 shared M. F. Kearney· 3 shared E. K. Halvas· 2 shared J. M. Coffin· 2 shared J. Spindler· 2 shared M. J. Bale· 2 shared W. Shao· 2 shared A. A. Capoferri· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

J. W. Mellors

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA

A. A. Capoferri, A. Wiegand, F. Hong, J. L. Jacobs, J. Spindler, A. Musick, M. J. Bale, W. Shao, M. D. Sobolewski, A. R. Cillo, B. T. Luke, C. M. Fennessey, R. J. Gorelick, R. Hoh, E. K. Halvas, , M. F. Kearney

The paper compares the fraction and total number of HIV-infected cells with unspliced RNA in controllers and non-controllers, finding that viremic control is linked to fewer infected cells, not a lower fraction of infected cells with HIV usRNA.

bioRxiv · Jul 1, 2024Microbiology

Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children

M. J. Bale, M. G. Katusiime, D. Wells, X. Wu, J. Spindler, E. K. Halvas, J. C. Cyktor, A. Wiegand, W. Shao, M. F. Cotton, S. H. Hughes, J. W. Mellors, J. M. Coffin, G. U. Van Zyl, M. F. Kearney

This study identifies early emergence and long-term persistence of HIV-infected T cell clones in children on antiretroviral therapy, with proviral integration in proto-oncogenes.

bioRxiv · Sep 15, 2020Microbiology

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

Y. Hikichi, R. Van Duyne, P. Pham, J. L. Groebner, A. Wiegand, J. W. Mellors, M. F. Kearney, E. O. Freed

This study shows that HIV-1 envelope glycoprotein mutations can confer broad antiretroviral resistance through cell-cell transmission and structural changes, independent of target-gene mutations.

bioRxiv · Aug 6, 2020Microbiology