On optimal temozolomide scheduling for slowly growing gliomas
B. Segura-Collar, J. Jimenez-Sanchez, R. Gargini, M. Dragoj, J. M. Sepulveda, M. Pesic, P. Sanchez-Gomez, V. M. Perez-Garcia
This study uses in-silico models and experimental data to show that longer TMZ dose intervals improve survival and reduce toxicity in slowly growing gliomas by altering tumor phenotype.
bioRxiv · Mar 10, 2022 · PreprintCancer Biology