Author

J. MacGurn

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Cell Biology· 1

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Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

J. K. A. Macedo· 1 shared K. Liu· 1 shared L. E. A. Young· 1 shared N. L. Hepowit· 1 shared R. C. Dickson· 1 shared R. C. Sun· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

J. K. A. Macedo

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1 paper

Recent·Most cited

Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools

N. L. Hepowit, J. K. A. Macedo, L. E. A. Young, K. Liu, R. C. Sun, J. MacGurn, R. C. Dickson

This study shows that pharmacologically lowering amino acid pools in yeast extends lifespan by inhibiting TORC1 signaling through sphingolipid-dependent mechanisms.

bioRxiv · Oct 30, 2020Cell Biology