M. Nomura

Rapid spread of a vertically transmitted symbiont induces drastic shifts in butterfly sex ratio

The paper tracks the rapid spread of Wolbachia in a butterfly population, causing a drastic shift from a 1:1 sex ratio to a female-biased ratio of 94.4% in 4 years.

Convergent reductive evolution of cyanobacteria in symbiosis with Dinophysiales dinoflagellates

This study sequenced a cyanobacterial symbiont of a dinoflagellate, revealing convergent genome reduction and shared features with another symbiont, while identifying unique genomic islands.

A ketogenic diet reduces age-induced chronic neuroinflammation in mice

This study shows that a cyclic ketogenic diet reduces neuroinflammation in aging mice by modulating microglial responses to inflammatory stimuli.

Integrative spatial analysis reveals a multi-layered organization of glioblastoma

This study uses spatial transcriptomics and proteomics to reveal three modes of cellular organization in glioblastoma, with hypoxia driving a 5-layered global architecture.

β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain

This study identifies β-hydroxybutyrate as a metabolic regulator of protein solubility in aging and Alzheimer's disease, showing it reduces insolubility of pathological proteins like amyloid-β.

Ketone body metabolism declines with age in mice in a sex-dependent manner

This study shows that ketone body metabolism declines with age in mice, with sex-dependent differences in metabolic responses to a ketogenic diet.

Evaluation of the Efficacy and Safety of a Clinical Grade Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Patch: A Pre-Clinical Study

This pre-clinical study evaluates the safety and efficacy of clinical-grade human iPSC-derived cardiomyocyte patches in treating heart failure, showing improved cardiac function and no adverse effects.

Persistence of a Wolbachia-driven sex ratio bias in an island population of Eurema butterflies

The paper shows that a Wolbachia strain causing female-biased sex ratios persists in an Eurema mandarina population for over 12 years, with stable coexistence of infected and uninfected females.

Large DNA virus promoted the endosymbiotic evolution to make a photosynthetic eukaryote

This study shows that a large DNA virus played a key role in the rapid genome reorganization and gene transfer during the endosymbiotic evolution of a photosynthetic amoeba.

Can we predict which species win when new habitat becomes available?

This study examines how geographic, climatic, and trait factors influence the ability of open-habitat plant species to colonize newly opened habitats created by deforestation.