Author

J. R. Gould

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. D. Meshram· 1 shared E. I. Frolova· 1 shared E. K. Leonard· 1 shared E. R. Johansen· 1 shared F. Dominguez· 1 shared I. Frolov· 1 shared J. B. Spangler· 1 shared J. Tomala· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

C. D. Meshram

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity

E. K. Leonard, J. Tomala, J. R. Gould, M. I. Leff, J.-X. Lin, P. Lin, M. J. Porter, E. R. Johansen, L. Thompson, S. D. Cao, T. Henclova, M. Huliciak, O. Vanek, M. Kovar, W. J. Leonard, J. B. Spangler

This paper develops an IL-2/antibody fusion protein that enhances immune effector cell activation and antitumor activity while reducing toxicity compared to natural IL-2.

bioRxiv · May 3, 2023Bioengineering

NAP1L1 and NAP1L4 binding to Hypervariable Domain of Chikungunya Virus nsP3 Protein is bivalent and requires phosphorylation

F. Dominguez, N. Shiliaev, T. Lukash, P. Agback, O. Palchevska, J. R. Gould, C. D. Meshram, P. E. Prevelige, T. J. Green, T. Agback, E. I. Frolova, I. Frolov

This study identifies NAP1L1 and NAP1L4 as host factors that bind to the phosphorylated hypervariable domain of CHIKV nsP3, enhancing viral replication through bivalent interactions.

bioRxiv · May 19, 2021Microbiology