Author

J. R. Groom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Sheikh· 1 shared A. D. Luster· 1 shared A. Hughson· 1 shared A. M. Livingstone· 1 shared A. McGurk· 1 shared A. Zaini· 1 shared C. Zaph· 1 shared D. J. Fowell· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. A. Sheikh

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response

A. Zaini, L. Dalit, A. A. Sheikh, D. Thiele, Y. Zhang, J. Runting, G. Rodrigues, J. Ng, M. Bramhall, S. Scheer, L. Hailes, J. R. Groom, K. L. Good-Jacobson, C. Zaph

This study identifies distinct Tfh cell populations during chronic and acute helminth infections and shows their role in type 2 immune responses.

bioRxiv · Oct 20, 2021Immunology

CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

H. Prizant, N. Patil, S. Negatu, A. McGurk, S. A. Leddon, A. Hughson, T. D. McRae, Y. Gao, A. M. Livingstone, J. R. Groom, A. D. Luster, D. J. Fowell

The paper identifies CXCL10+ perivascular clusters as Th1 activation niches that enhance T cell-APC interactions through IFN-gamma-dependent feedback.

bioRxiv · Oct 4, 2020Immunology