G. Rodrigues

3-Nitropropionic acid induces histological and behavioral alterations in adult zebrafish: role of antioxidants on behavioral dysfunction

This study shows that 3-NPA induces neurodegeneration in adult zebrafish and that vitamin C, creatine, and melatonin mitigate HD-like behavioral issues.

An explainable machine learning data analytics method using TIGIT-linked genes for identifying biomarker signatures to clinical outcomes.

The paper develops an explainable machine learning model using TIGIT-linked genes to predict survival outcomes in breast cancer patients.

Identification of Sequence Determinants for the ABHD14 Enzymes

This study identifies key sequence determinants for ABHD14A and ABHD14B enzymes through bioinformatics and biochemical experiments, enabling better classification and evolutionary mapping.

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution

This study shows that circulating tumor extracellular vesicles can be used to monitor genomic and transcriptomic changes in metastatic prostate cancer through liquid biopsy.

Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response

This study identifies distinct Tfh cell populations during chronic and acute helminth infections and shows their role in type 2 immune responses.

c-Rel is required for IL-33-dependent activation of ILC2s

This study identifies c-Rel as essential for IL-33-dependent activation of ILC2s, showing its role in lung inflammation and cytokine production.

Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

This study identifies cholesteryl hemiazelate as a cause of lysosome dysfunction and exocytosis in macrophages, contributing to atherosclerosis.

The methyltransferase DOT1L limits activation and the Th1 program in CD4+ T cells during infection and inflammation

This study shows that DOT1L limits Th1 activation and lineage stability in CD4+ T cells, with implications for immune response regulation.