Author

K. L. Good-Jacobson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Szeto· 2 shared C. Zaph· 2 shared L. Cooper· 2 shared L. Dalit· 2 shared L. Hailes· 2 shared S. Gras· 2 shared S. Scheer· 2 shared A. A. Sheikh· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

C. Szeto

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

L. Cooper, H. Xu, J. Polmear, C. Szeto, E. S. Pang, M. Gupta, J. J. Taylor, K. J. L. Jackson, A. Nguyen, N. La Gruta, L. G. Martelotto, I. A. Parish, M. O'Keeffe, C. D. Scharer, S. Gras, K. L. Good-Jacobson

The paper identifies type I interferon dynamics as a key factor shaping memory B cell development during chronic viral infection and shows that early IFNAR-1 blockade can reverse chromatin changes.

bioRxiv · Mar 2, 2023Immunology

COVID-19 vaccine booster induces a strong CD8+ T cell response against Omicron variant epitopes in HLA-A*02:01+ individuals

A. T. Nguyen, C. Szeto, D. S. M. Chatzileontiadou, Z. W. M. Tong, M. J. Dewar-Oldis, L. Cooper, L. D. Murdolo, K. Y. Chew, K. E. Lineburg, A. Riboldi-Tunicliffe, R. Williamson, B. J. Gardiner, D. Jayasinghe, C. A. Lobos, Y. M. Ahn, , S. Gras

bioRxiv · Jan 12, 2022 · PreprintImmunology

Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response

A. Zaini, L. Dalit, A. A. Sheikh, D. Thiele, Y. Zhang, J. Runting, G. Rodrigues, J. Ng, M. Bramhall, S. Scheer, L. Hailes, J. R. Groom, K. L. Good-Jacobson, C. Zaph

This study identifies distinct Tfh cell populations during chronic and acute helminth infections and shows their role in type 2 immune responses.

bioRxiv · Oct 20, 2021Immunology

The histone methyltransferase DOT1L is essential for humoral immune responses

L. Kealy, A. Di Pietro, L. Hailes, S. Scheer, L. Dalit, J. Groom, C. Zaph, K. L. Good-Jacobson

This study shows that DOT1L is essential for B cell development and humoral immune responses, as its deletion leads to impaired germinal center formation and reduced antibody production.

bioRxiv · Jun 19, 2020Immunology